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Job Details
Posted date: May 29, 2026
There have been 231 jobs posted with the title of Principal Product Manager - Technical all time at Amazon.There have been 231 Principal Product Manager - Technical jobs posted in the last month.
Location: Seattle, WA
Estimated salary: $211,650
Range: $179,900 - $243,400
Description
As part of the AWS Applied AI Solutions organization, we have a vision to provide business applications, leveraging Amazon’s unique experience and expertise, that are used by millions of companies worldwide to manage day-to-day operations. We will accomplish this by accelerating our customers’ businesses through delivery of intuitive and differentiated technology solutions that solve enduring business challenges. We blend vision with curiosity and Amazon’s real-world experience to build opinionated, turnkey solutions. Where customers prefer to buy over build, we become their trusted partner with solutions that are no-brainers to buy and easy to use.Are you passionate about leveraging AI to revolutionize life sciences? AWS Life Sciences Applied AI is seeking a visionary Principal Product Manager to lead the development of applications that reimagine how clinical trials are designed, executed, and delivered.
Key job responsibilities
As Principal Product Manager, you'll lead pioneering product development for AI-driven clinical trials transformation. You'll guide a team of builders (product managers, developers, and scientists) to invent and simplify on behalf of pharmaceutical companies, biotech firms, and clinical operations teams—defining novel, generative AI agent-based experiences that help them accelerate the path from discovery to treatment. You will drive innovation by reimagining how clinical evidence is generated and how trial operations are managed, replacing fragmented manual processes with intelligent, continuously learning systems. This is a highly visible and impactful role within AWS, offering the opportunity to shape the future of clinical development and drive innovation at a global scale. You will be responsible for defining key product directions, adopting or inventing new machine learning techniques, reimagining user workflows and experiences, and fundamentally changing how life-saving therapies reach patients.
About the team
ABOUT AWS:
Diverse Experiences
Amazon values diverse experiences. Even if you do not meet all of the preferred qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn’t followed a traditional path, or includes alternative experiences, don’t let it stop you from applying.
Why AWS
Amazon Web Services (AWS) is the world’s most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating — that’s why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses.
Work/Life Balance
We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why flexible work hours and arrangements are part of our culture. When we feel supported in the workplace and at home, there’s nothing we can’t achieve in the cloud.
Inclusive Team Culture
Here at AWS, it’s in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity and AmazeCon conferences, inspire us to never stop embracing our uniqueness.
Mentorship and Career Growth
We’re continuously raising our performance bar as we strive to become Earth’s Best Employer. That’s why you’ll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional.
Qualifications
- Bachelor's degree- Experience owning/driving roadmap strategy and definition
- Experience with feature delivery and tradeoffs of a product
- Experience technical product management
Extended Qualifications
- Experience working directly with Engineers on product enhancements- Experience in project management methodologies, business analysis, or process improvement
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.
The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.
USA, WA, Seattle - 179,900.00 - 243,400.00 USD annually